Before Sildenafil was well known for its popularity as the blue diamond-shaped drug Viagra to treat men who suffer from erectile dysfunction, Sildenafil (Pfizer) was an FDA-approved medication used to combat pulmonary arterial hypertension in both men and women. Pulmonary arterial hypertension is a condition where the pulmonary arteries stop effectively pumping blood through the arteries to the rest of the body. Sildenafil, as a phosphodiesterase type 5 (PDE5) inhibitor, works to control the vessels in the body in how wide or narrow they are. PDE5, the enzyme most known for increasing and improving blood flow to the penis for the treatment of erectile dysfunction, also decreases arterial resistance and pressure by opening up the blood vessels. Revatio is the name for Sildenafil when it is used in the treatment of pulmonary arterial hypertension.

How Revatio works in the treatment of pulmonary arterial hypertension?

When the body’s pulmonary arteries are no longer effectively pumping blood throughout the body, the PDE5 in Sildenafil works to increase blood flow. For those suffering from erectile dysfunction, it results in harder, long-lasting erections due to increased blood flow to the penis. However, for those individuals who suffer from pulmonary arterial hypertension, the PDE5 works to get rid of symptoms associated with strokes and heart attacks, such as, fainting, shortness of breath, dizziness, and possible heart failure. Blood flow is increased, allowing blood vessels to relax and allow for oxygen and blood to travel the body freely.

How else does Revatio differ from Viagra?

Both drugs, Revatio and Viagra, have Sildenafil in it and both are used to increase blood flow to the body, so the question is where they are different? First, the physical shapes of the medications are different – Revatio medication is round and white, whereas Viagra is diamond-shaped and blue. Another difference is in the dosage people take for both drugs. People suffering from pulmonary arterial hypertension are told to take the recommended dose of 20mg three times a day, four to six hours apart. Viagra, however, can be taken in dosages ranging from 25mg to 100mg, and it is highly recommended that Viagra not be taking more than once within a 24 hour period. Lastly, whereas you can order Viagra online, you can only get Revatio with a doctor’s prescription.

A quick primer on what else Revatio treats

As it has already been stated, Sildenafil can help to treat men with erectile dysfunction and people who suffer from pulmonary aerial hypertension, but are there other conditions that the Sildenafil in Revatio can treat? Though not FDA-approved, and there are still medical studies and clinical trials going on, Revatio can also prevent and treat high altitude pulmonary edema, which is associated with people who suffer from altitude sickness. It is becoming more commonplace that doctors are now prescribing Revatio to frequent flyers and mountain climbers for the decent, either in the air or down the mountain. In regards to flying as well, there is current research to prove whether or not Revatio can help people who suffer from jet lag. Athletes are also known for asking for prescriptions for Revatio as it can improve athletic performance through the opening of blood vessels which make their muscles expand.

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